Tsukasa Nozu Selected Research

Levodopa (L Dopa)

2/2016

Levodopa acts centrally to induce an antinociceptive action against colonic distension through activation of D2 dopamine receptors and the orexinergic system in the brain in conscious rats.

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Tsukasa Nozu Research Topics

Disease

24	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 04/2024 - 02/2015
18	Hypersensitivity (Allergy) 04/2024 - 08/2006
12	Hyperalgesia 01/2020 - 12/2014
6	Visceral Pain 04/2024 - 07/2005
4	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2020 - 04/2011
4	Nociceptive Pain 01/2018 - 02/2016
2	Fever (Fevers) 12/2023 - 06/2022
2	Hypertension (High Blood Pressure) 04/2022 - 01/2008
2	Sepsis (Septicemia) 08/2021 - 12/2020
2	Bullous Pemphigoid (Pemphigoid) 10/2016 - 01/2010
1	Dementia (Dementias) 04/2024
1	Aphthous Stomatitis (Aphthous Ulcer) 12/2023
1	Lymphadenitis (Adenitis) 12/2023
1	Pharyngitis (Sore Throat) 12/2023
1	Ileus 11/2023
1	Neuroinflammatory Diseases 09/2023
1	Autistic Disorder (Autism) 10/2022
1	Familial Mediterranean Fever (Periodic Disease) 06/2022
1	Diarrhea 06/2022
1	Inflammation (Inflammations) 04/2022
1	Insulin Resistance 04/2022
1	Dysbiosis 04/2022
1	Obesity 04/2022
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 04/2022
1	Dyslipidemias (Dyslipidemia) 04/2022
1	Pain (Aches) 01/2020
1	Familial cyclic vomiting syndrome 02/2014
1	Thyroid Neoplasms (Thyroid Cancer) 01/2011
1	Hyponatremia 01/2011
1	Hypothyroidism 01/2011
1	Pyelonephritis 01/2010

Drug/Important Bio-Agent (IBA)

17	LipopolysaccharidesIBA 09/2023 - 01/2017
11	Corticotropin-Releasing HormoneIBA 09/2023 - 08/2006
11	CytokinesIBA 08/2022 - 01/2017
5	OrexinsIBA 09/2023 - 04/2011
5	Corticotropin-Releasing Hormone Receptors (Corticotropin Releasing-Hormone Receptor)IBA 08/2022 - 12/2014
4	Colchicine FDA LinkGeneric 12/2023 - 12/2020
4	Interleukin-1 (Interleukin 1)IBA 11/2023 - 12/2015
4	Toll-Like Receptor 4IBA 09/2023 - 11/2018
4	Naloxone (Narcan)FDA LinkGeneric 07/2021 - 01/2018
3	GhrelinIBA 11/2023 - 01/2020
3	astressinIBA 08/2022 - 12/2017
2	Butyrates (Butyrate)IBA 04/2024 - 12/2019
2	PhlorhizinIBA 11/2023 - 07/2021
2	Oxytocin (Pitocin)FDA LinkGeneric 09/2023 - 10/2022
2	NeuropeptidesIBA 09/2023 - 01/2020
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 08/2022 - 11/2018
2	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 08/2022 - 11/2018
2	Toll-Like Receptors (Toll-Like Receptor)IBA 04/2022 - 07/2021
2	Evans Blue (Blue, Evans)FDA Link 07/2021 - 11/2020
2	Adenosine (Adenocard)FDA LinkGeneric 01/2020 - 03/2016
2	NG-Nitroarginine Methyl Ester (L-NAME)IBA 01/2019 - 01/2018
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019 - 01/2018
2	Interleukin-6 (Interleukin 6)IBA 12/2017 - 01/2017
1	Anti-Allergic Agents (Antiallergic Agents)IBA 04/2024
1	InflammasomesIBA 04/2024
1	tranilastIBA 04/2024
1	Histamine (Histamine Dihydrochloride)FDA Link 04/2024
1	Therapeutic UsesIBA 09/2023
1	imegliminIBA 09/2023
1	ProstaglandinsIBA 01/2023
1	beraprostIBA 01/2023
1	Epoprostenol (Prostacyclin)FDA LinkGeneric 01/2023
1	ApelinIBA 08/2022
1	ethyl 6- (N- (2- chloro- 4- fluorophenyl)sulfamoyl)cyclohex- 1- ene- 1- carboxylateIBA 08/2022
1	EMA400IBA 07/2021
1	Type 2 Angiotensin ReceptorIBA 07/2021
1	Cholinergic Agents (Cholinergics)IBA 12/2020
1	Imipramine (Janimine)FDA LinkGeneric 11/2020
1	Dopamine D2 Receptor AntagonistsIBA 01/2020
1	Dopamine D1 Receptors (Dopamine D1 Receptor)IBA 01/2020
1	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 01/2020
1	CB2 Cannabinoid ReceptorIBA 01/2020
1	Losartan (Cozaar)FDA LinkGeneric 01/2020
1	Butyric Acid (Butanoic Acid)IBA 12/2019
1	Grape Seed ExtractIBA 11/2019
1	Dehydroepiandrosterone SulfateIBA 06/2019
1	Dehydroepiandrosterone (DHEA)IBA 06/2019
1	Metformin (Glucophage)FDA LinkGeneric 01/2019
1	Protein Kinase InhibitorsIBA 01/2019
1	Pioglitazone (Actos)FDA Link 01/2019
1	Adenosine Monophosphate (AMP)IBA 01/2019
1	eritoranIBA 11/2018
1	Lovastatin (Mevacor)FDA LinkGeneric 01/2018
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2018
1	mevalonolactoneIBA 01/2018
1	Liraglutide FDA Link 01/2018
1	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2018
1	Levodopa (L Dopa)FDA LinkGeneric 02/2016
1	CRF receptor type 1IBA 08/2015
1	Sumatriptan (Imigran)FDA LinkGeneric 02/2014
1	Peptides (Polypeptides)IBA 04/2011
1	Thyroid HormonesIBA 01/2011
1	IodineIBA 01/2011
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2010

Therapy/Procedure

3	Therapeutics 06/2022 - 01/2010
2	Subcutaneous Injections 01/2020 - 11/2018
2	Gastrostomy 10/2016 - 01/2010
1	Fecal Microbiota Transplantation 01/2023
1	Length of Stay 01/2010